NKD1

Across TCGA patient cohorts, NKD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,142 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NKD1-associated proteins across cancer lineages are VCAN, SEPTIN7, and HMCN1. Each is linked with NKD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both NKD1-to-partner and partner-to-NKD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NKD1 versus VCAN in OV, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NKD1→partner) and Y-score (partner→NKD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VCAN →	+1.601	+1.584	<.001	<.001	3	7
PDAC	SEPTIN7 →	+0.313	+0.738	<.001	.002	2	8
BRCA	HMCN1 →	+0.679	+0.509	<.001	<.001	3	7
BRCA	HSPG2 →	+0.479	+0.617	<.001	<.001	3	7
OV	ILK →	+0.506	+1.346	<.001	<.001	3	7
OV	ANTXR1 →	+0.729	+1.371	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,142 associations by consensus.

NKD1 vs VCAN — OV

Explore this scatter interactively →