NKD1

Across TCGA cell cohorts, NKD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,618 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NKD1-associated GO terms across cancer lineages are Nucleoside triphosphate biosynthetic process, Purine nucleoside triphosphate biosynthetic process, and Purine ribonucleoside triphosphate biosynthetic process. Each is linked with NKD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both NKD1-to-partner and partner-to-NKD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside triphosphate biosynthetic process grouped by NKD1-low versus NKD1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NKD1→partner) and Y-score (partner→NKD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Nucleoside triphosphate biosynthetic process →	+0.100	+1.157	<.001	<.001	3	8
SKIN	Purine nucleoside triphosphate biosynthetic process →	+0.099	+1.024	<.001	.001	3	8
SKIN	Purine ribonucleoside triphosphate biosynthetic process →	+0.099	+1.024	<.001	.001	3	8
OVARY	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.174	+0.467	<.001	<.001	3	7
BLOOD_Leukemia	Response to arsenic-containing substance →	+0.079	+0.179	<.001	.007	3	7
BLOOD_Lymphoma	Purine nucleotide biosynthetic process →	+0.057	+0.259	.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,618 associations by consensus.

Nucleoside triphosphate biosynthetic process by NKD1 expression — SKIN

Explore this box plot interactively →