NIT2

Across TCGA patient cohorts, NIT2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,338 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NIT2-associated genes across cancer lineages are WDR5B, NEK11, and RPL24. Each is linked with NIT2 in more than 6 cancer types. Because this analysis shows association rather than direction, both NIT2-to-partner and partner-to-NIT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NIT2 versus WDR5B in LSCC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIT2→partner) and Y-score (partner→NIT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR5B →	+0.535	+0.356	<.001	<.001	3	7
BRCA	NEK11 →	+0.564	+0.284	<.001	<.001	3	6
OV	RPL24 →	+0.535	+0.284	.006	.003	3	5
LSCC	EIF2A →	+0.540	+0.327	<.001	.003	3	5
CCRCC	TOMM70 →	+0.762	+0.506	<.001	<.001	3	5
OV	RIOX2 →	+0.673	+0.392	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,338 associations by consensus.

NIT2 vs WDR5B — LSCC

Explore this scatter interactively →