NINJ1

Across TCGA patient cohorts, NINJ1 mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NINJ1-associated genes across cancer lineages are NUTF2P8, RN7SL248P, and AQP7P2. Each is linked with NINJ1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NINJ1-to-partner and partner-to-NINJ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NUTF2P8 grouped by NINJ1-low versus NINJ1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NINJ1→partner) and Y-score (partner→NINJ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUTF2P8 →	+0.129	+3.246	.001	.008	3	1
UCEC	RN7SL248P →	+0.102	+4.137	<.001	.008	3	1
UCEC	AQP7P2 →	+0.215	+2.747	<.001	.009	3	1
UCEC	TEX43 →	+0.544	+3.121	<.001	.004	3	1
UCEC	RNU6-222P →	+0.906	+3.224	<.001	.004	3	1
UCEC	RNA5SP405 →	+0.442	+3.997	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

NUTF2P8 by NINJ1 expression — UCEC

Explore this box plot interactively →