NIFK

Across TCGA patient cohorts, NIFK protein abundance is significantly associated with the RNA expression of many other genes, with 19,857 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NIFK-associated genes across cancer lineages are HROB, FANCI, and WDR43. Each is linked with NIFK in more than 7 cancer types. Because this analysis shows association rather than direction, both NIFK-to-partner and partner-to-NIFK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NIFK versus HROB in LSCC, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIFK→partner) and Y-score (partner→NIFK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HROB →	+0.849	+0.356	<.001	<.001	3	8
LSCC	FANCI →	+0.720	+0.253	<.001	<.001	3	8
LSCC	WDR43 →	+0.749	+0.312	<.001	<.001	3	8
LSCC	NME1 →	+0.640	+0.351	<.001	<.001	3	8
LUAD	CLSPN →	+0.779	+0.279	<.001	<.001	3	8
UCEC	OIP5 →	+0.679	+0.235	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,857 associations by consensus.

NIFK vs HROB — LSCC

Explore this scatter interactively →