NIFK

Across TCGA patient cohorts, NIFK mutation is significantly associated with the RNA expression of many other genes, with 792 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NIFK-associated genes across cancer lineages are RNA5SP410, RN7SL357P, and GPR32P1. Each is linked with NIFK in more than 2 cancer types. Because this analysis shows association rather than direction, both NIFK-to-partner and partner-to-NIFK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP410 grouped by NIFK-low versus NIFK-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIFK→partner) and Y-score (partner→NIFK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNA5SP410 →	+0.417	+7.503	<.001	<.001	3	3
BLCA	RN7SL357P →	+0.142	+5.251	.002	.006	3	2
BLCA	GPR32P1 →	+0.182	+5.588	<.001	.004	3	2
UCEC	RN7SL354P →	+0.225	+2.084	<.001	.001	3	2
UCEC	ZFP91-CNTF →	+0.030	+1.808	<.001	.007	3	2
COAD	RNU6-128P →	+0.596	+4.418	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 792 associations by consensus.

RNA5SP410 by NIFK expression — LIHC

Explore this box plot interactively →