NIFK

Across TCGA cell cohorts, NIFK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,356 significant associations in total. CNS shows the largest number of these associations.

The most reproducible NIFK-associated GO terms across cancer lineages are RNA 5'-end processing, Maturation of SSU-rRNA, and Mitochondrial tRNA modification. Each is linked with NIFK in more than 16 cancer types. Because this analysis shows association rather than direction, both NIFK-to-partner and partner-to-NIFK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA 5'-end processing grouped by NIFK-low versus NIFK-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NIFK→partner) and Y-score (partner→NIFK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	RNA 5'-end processing →	+0.098	+1.146	.001	<.001	3	17
BONE	Maturation of SSU-rRNA →	+0.109	+0.576	<.001	.002	3	16
LUNG_NSCLC_LUAD	Mitochondrial tRNA modification →	+0.104	+0.767	<.001	<.001	3	16
CNS	tRNA processing →	+0.051	+0.535	<.001	<.001	3	16
BONE	Maturation of LSU-rRNA →	+0.138	+0.514	.002	.009	2	17
UPPER_AERODIGESTIVE_TRACT	Mitochondrial gene expression →	+0.105	+0.745	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,356 associations by consensus.

RNA 5'-end processing by NIFK expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →