NGRN

Across TCGA patient cohorts, NGRN protein abundance is significantly associated with the RNA expression of many other genes, with 4,913 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NGRN-associated genes across cancer lineages are HECA, BNIP3L, and TLE4. Each is linked with NGRN in more than 3 cancer types. Because this analysis shows association rather than direction, both NGRN-to-partner and partner-to-NGRN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NGRN versus HECA in BRCA, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NGRN→partner) and Y-score (partner→NGRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HECA →	-0.478	-0.396	<.001	<.001	3	4
BRCA	BNIP3L →	-0.549	-0.285	.001	.005	3	3
BRCA	TLE4 →	-0.535	-0.313	<.001	<.001	3	3
BRCA	SH3PXD2A →	-0.680	-0.420	<.001	<.001	3	3
BRCA	OSBPL9 →	-0.462	-0.391	<.001	<.001	3	3
CCRCC	CNRIP1 →	-0.527	-0.246	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,913 associations by consensus.

NGRN vs HECA — BRCA

Explore this scatter interactively →