NFYC

Across TCGA patient cohorts, NFYC RNA expression is significantly associated with the protein abundance of many other proteins, with 8,956 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NFYC-associated proteins across cancer lineages are HNRNPU, PPIH, and HTATSF1. Each is linked with NFYC in more than 5 cancer types. Because this analysis shows association rather than direction, both NFYC-to-partner and partner-to-NFYC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFYC versus HNRNPU in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NFYC→partner) and Y-score (partner→NFYC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HNRNPU →	+0.202	+0.260	<.001	<.001	3	6
BRCA	PPIH →	+0.304	+0.484	<.001	<.001	3	5
GBM	HTATSF1 →	+0.320	+0.220	.003	.007	3	5
LSCC	CDC73 →	+0.225	+0.264	<.001	<.001	3	5
BRCA	ERI3 →	+0.379	+0.443	<.001	<.001	3	5
LSCC	TOE1 →	+0.339	+0.379	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,956 associations by consensus.

NFYC vs HNRNPU — GBM

Explore this scatter interactively →