NFYC

Across TCGA patient cohorts, NFYC protein abundance is significantly associated with the RNA expression of many other genes, with 11,864 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NFYC-associated genes across cancer lineages are LUC7L3, EZH1, and RBMX. Each is linked with NFYC in more than 5 cancer types. Because this analysis shows association rather than direction, both NFYC-to-partner and partner-to-NFYC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NFYC versus LUC7L3 in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFYC→partner) and Y-score (partner→NFYC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LUC7L3 →	+0.608	+0.277	<.001	<.001	3	6
LSCC	EZH1 →	+0.472	+0.294	<.001	<.001	3	6
GBM	RBMX →	+0.487	+0.379	<.001	<.001	3	6
LSCC	MBTD1 →	+0.481	+0.221	<.001	<.001	3	5
COAD	TUT4 →	+0.578	+0.308	<.001	<.001	3	5
COAD	CNNM3 →	+0.602	+0.235	.001	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,864 associations by consensus.

NFYC vs LUC7L3 — LSCC

Explore this scatter interactively →