NFYC

Across TCGA cell cohorts, NFYC RNA expression is significantly associated with the go_rna of many other GO terms, with 4,536 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NFYC-associated GO terms across cancer lineages are Positive regulation of cytokinesis, Spindle midzone assembly, and mRNA 3'-end processing. Each is linked with NFYC in more than 12 cancer types. Because this analysis shows association rather than direction, both NFYC-to-partner and partner-to-NFYC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytokinesis grouped by NFYC-low versus NFYC-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFYC→partner) and Y-score (partner→NFYC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of cytokinesis →	+0.119	+0.942	.003	<.001	3	13
BREAST	Spindle midzone assembly →	+0.237	+0.858	<.001	<.001	3	13
BONE	mRNA 3'-end processing →	+0.103	+0.875	.001	.001	3	13
BONE	Double-strand break repair →	+0.065	+0.605	<.001	.001	3	13
BLOOD_Leukemia	Negative regulation of cell cycle process →	+0.063	+0.630	<.001	<.001	3	12
BLOOD_Leukemia	Regulation of chromatin organization →	+0.102	+0.655	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,536 associations by consensus.

Positive regulation of cytokinesis by NFYC expression — BREAST

Explore this box plot interactively →