NFKBID

Across TCGA cell cohorts, NFKBID mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NFKBID-associated genes across cancer lineages are ALPI, TEX48, and MYH4. Each is linked with NFKBID in more than 1 cancer types. Because this analysis shows association rather than direction, both NFKBID-to-partner and partner-to-NFKBID results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ALPI grouped by NFKBID-low versus NFKBID-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFKBID→partner) and Y-score (partner→NFKBID) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ALPI →	+0.004	+4.201	<.001	.001	3	1
BLOOD_Leukemia	TEX48 →	+0.025	+3.475	<.001	.006	3	1
BLOOD_Leukemia	MYH4 →	+0.003	+3.969	<.001	.009	3	1
BLOOD_Leukemia	TP53TG3E →	+0.020	+3.289	.005	.009	3	1
LARGE_INTESTINE	BEND2 →	+0.032	+4.977	<.001	.007	3	1
LARGE_INTESTINE	TECRL →	+0.026	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ALPI by NFKBID expression — BLOOD_Leukemia

Explore this box plot interactively →