NFKBID

Across TCGA pan-cancer cohorts, NFKBID RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of NFKBID’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NFKBID RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NFKBID is over-expressed in tumor, although a few such as BRCA and LUSC show the opposite, repressed pattern.

KIRC, BRCA, and COAD are the cancer types where NFKBID tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NFKBID RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	IV	+1.117	<.001	10	view →
BRCA	Female	II,III,IV	−0.447	<.001	8	view →
COAD	Female	All	+0.619	<.001	7	view →
CHOL	All	All	+1.312	<.001	5	view →
LUSC	All	All	−0.660	<.001	5	view →
KICH	All	All	−0.657	.002	5	view →
STAD	All	II,III,IV	+0.591	.007	4	view →
LUAD	All	All	−0.461	<.001	3	view →
KIRP	All	IV	+0.922	.027	2	view →
ESCA	Female	All	+0.876	.024	2	view →
LIHC	All	II,III,IV	+0.387	.005	2	view →
THCA	Female	All	−0.340	.018	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

NFKBID–KIRC

Open the KIRC breakdown →