Q-omics provides the consensus-scored NFIA-AS1 profile across patient tissues and cancer cell-line models. NFIA-AS1 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, NFIA-AS1 is differentially expressed in 5, with the highest sampling consensus in KIRC. Additionally, NFIA-AS1 RNA expression shows 13,628 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight ACC, KIRC, and GBM as cancer lineages where NFIA-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NFIA-AS1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NFIA-AS1 survival associations across molecular data types. NFIA-AS1 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NFIA-AS1 RNA expression–survival associations across cancer types. High NFIA-AS1 expression shows unfavorable associations in KICH, READ, UCEC and UVM, but favorable associations in ACC and UCS. The ACC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for NFIA-AS1 RNA expression.
This table summarizes NFIA-AS1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for NFIA-AS1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NFIA-AS1 shows lower tumor expression in THCA and HNSC and higher tumor expression in KIRC, BRCA and KICH. The KIRC box plot shows higher NFIA-AS1 RNA expression in tumor versus normal tissue (log2 FC = +0.242, t-test p < 0.001).
This table shows molecular features associated with NFIA-AS1 in patient tissues and cancer cell lines. In patient samples, NFIA-AS1 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
