NFE2L1

Across TCGA patient cohorts, NFE2L1 mutation is significantly associated with the RNA expression of many other genes, with 3,731 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NFE2L1-associated genes across cancer lineages are LINC01670, WDR45BP1, and LINC01370. Each is linked with NFE2L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NFE2L1-to-partner and partner-to-NFE2L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01670 grouped by NFE2L1-low versus NFE2L1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFE2L1→partner) and Y-score (partner→NFE2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LINC01670 →	+0.047	+4.868	.005	<.001	3	2
UCEC	WDR45BP1 →	+0.287	+2.863	.007	.001	3	2
BRCA	LINC01370 →	+0.389	+3.556	<.001	.006	3	2
BLCA	RN7SL612P →	+0.153	+3.683	.006	.003	3	2
CESC	GABRA6 →	+0.026	+3.653	<.001	.009	3	2
BRCA	OR8A2P →	+0.166	+3.396	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,731 associations by consensus.

LINC01670 by NFE2L1 expression — BRCA

Explore this box plot interactively →