NFATC4

Across TCGA cell cohorts, NFATC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,838 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NFATC4-associated GO terms across cancer lineages are Brain-derived neurotrophic factor receptor signaling pathway, Regulation of cell cycle G1/S phase transition, and Regulation of myoblast fusion. Each is linked with NFATC4 in more than 12 cancer types. Because this analysis shows association rather than direction, both NFATC4-to-partner and partner-to-NFATC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Brain-derived neurotrophic factor receptor signaling pathway grouped by NFATC4-low versus NFATC4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFATC4→partner) and Y-score (partner→NFATC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Brain-derived neurotrophic factor receptor signaling pathway →	+1.017	+1.807	<.001	<.001	3	13
BLOOD_Lymphoma	Regulation of cell cycle G1/S phase transition →	+0.047	+2.503	<.001	<.001	3	9
STOMACH	Regulation of myoblast fusion →	+0.118	+2.027	.007	.003	3	8
BLOOD_Lymphoma	Regulation of G1/S transition of mitotic cell cycle →	+0.053	+2.903	<.001	<.001	3	8
SKIN	Stress granule assembly →	+0.057	+1.415	.001	.001	3	8
STOMACH	Regulation of alternative mRNA splicing, via spliceosome →	+0.087	+1.710	.009	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,838 associations by consensus.

Brain-derived neurotrophic factor receptor signaling pathway by NFATC4 expression — OESOPHAGUS

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