NFATC2IP

Across TCGA cell cohorts, NFATC2IP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,708 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NFATC2IP-associated GO terms across cancer lineages are Double-strand break repair via homologous recombination, Regulation of DNA repair, and DNA replication. Each is linked with NFATC2IP in more than 18 cancer types. Because this analysis shows association rather than direction, both NFATC2IP-to-partner and partner-to-NFATC2IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair via homologous recombination grouped by NFATC2IP-low versus NFATC2IP-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NFATC2IP→partner) and Y-score (partner→NFATC2IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Double-strand break repair via homologous recombination →	+0.074	+0.838	<.001	<.001	3	19
SOFT_TISSUE	Regulation of DNA repair →	+0.084	+1.497	<.001	<.001	3	19
BONE	DNA replication →	+0.099	+0.621	<.001	.007	3	19
BONE	Signal transduction in response to DNA damage →	+0.080	+1.011	<.001	<.001	3	18
BONE	Positive regulation of DNA metabolic process →	+0.065	+0.630	<.001	.006	3	18
BONE	Double-strand break repair →	+0.071	+0.815	.004	.005	2	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,708 associations by consensus.

Double-strand break repair via homologous recombination by NFATC2IP expression — BLOOD_Myeloma

Explore this box plot interactively →