NEUROG3

Across TCGA patient cohorts, NEUROG3 mutation is significantly associated with the RNA expression of many other genes, with 778 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEUROG3-associated genes across cancer lineages are MIR3912, RNA5SP414, and PDE4B-AS1. Each is linked with NEUROG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEUROG3-to-partner and partner-to-NEUROG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3912 grouped by NEUROG3-low versus NEUROG3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEUROG3→partner) and Y-score (partner→NEUROG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR3912 →	+0.359	+3.797	<.001	.003	3	2
UCEC	RNA5SP414 →	+0.582	+2.554	<.001	<.001	3	2
LUSC	PDE4B-AS1 →	+0.168	+5.038	<.001	.009	3	2
LUSC	GAGE13 →	+0.426	+5.273	<.001	.006	3	2
COAD	FAM230H →	+0.005	+4.225	<.001	.007	3	1
COAD	MIR1277 →	+0.216	+4.821	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 778 associations by consensus.

MIR3912 by NEUROG3 expression — COAD

Explore this box plot interactively →