Q-omics provides the consensus-scored MIR1277 profile across patient tissues and cancer cell-line models. MIR1277 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, MIR1277 is differentially expressed in 1, with the highest sampling consensus in HNSC. Additionally, MIR1277 RNA expression shows 6,252 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight UVM, HNSC, and COAD as cancer lineages where MIR1277 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR1277 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR1277 survival associations across molecular data types. MIR1277 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR1277 RNA expression–survival associations across cancer types. High MIR1277 expression shows unfavorable associations in UVM, KIRP, LUSC, MESO and ESCA, but favorable associations in STAD. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for MIR1277 RNA expression.
This table summarizes MIR1277 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR1277. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR1277 shows higher tumor expression in HNSC. The HNSC box plot shows higher MIR1277 RNA expression in tumor versus normal tissue (log2 FC = +0.072, t-test p = .049).
This table shows molecular features associated with MIR1277 in patient tissues and cancer cell lines. In patient samples, MIR1277 shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.
