NEURL2

Across TCGA cell cohorts, NEURL2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NEURL2-associated genes across cancer lineages are CCDC172, POTEB, and TIFAB. Each is linked with NEURL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEURL2-to-partner and partner-to-NEURL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC172 grouped by NEURL2-low versus NEURL2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEURL2→partner) and Y-score (partner→NEURL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CCDC172 →	+0.094	+5.201	<.001	.006	3	1
BLOOD_Leukemia	POTEB →	+0.018	+4.922	<.001	.009	3	1
LARGE_INTESTINE	TIFAB →	+0.006	+4.977	<.001	.007	3	1
BLOOD_Lymphoma	DEFB126 →	+0.292	+3.714	<.001	.006	3	1
BLOOD_Lymphoma	GPR148 →	+0.381	+5.342	<.001	<.001	3	1
BLOOD_Lymphoma	SPATA31A7 →	+0.062	+3.523	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

CCDC172 by NEURL2 expression — BLOOD_Leukemia

Explore this box plot interactively →