Across TCGA cell cohorts, NEU4 mutation is significantly associated with the RNA expression of many other genes, with 85 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NEU4-associated genes across cancer lineages are FAM149A, C12orf57, and ULBP1. Each is linked with NEU4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEU4-to-partner and partner-to-NEU4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEU4→partner) and Y-score (partner→NEU4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FAM149A →	+0.818	+3.502	.003	.002	3	1
BLOOD_Leukemia	C12orf57 →	+1.029	+3.199	.005	.007	3	1
BLOOD_Leukemia	ULBP1 →	+1.502	+3.199	<.001	.007	3	1
BLOOD_Leukemia	LIFR →	+0.386	+2.697	<.001	.006	3	1
BLOOD_Leukemia	C9 →	+0.817	+2.676	<.001	.003	3	1
BLOOD_Leukemia	HPCAL4 →	+0.209	+2.825	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

Exploration

NEU4 survival (RNA) · tumor vs normal (RNA) · all NEU4 data types