Across TCGA cell cohorts, NEU4 mutation is significantly associated with the mutation status of many other genes, with 1,914 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NEU4-associated genes across cancer lineages are PDZD2, SRRT, and EIF4G3. Each is linked with NEU4 in more than 4 cancer types. Because this analysis shows association rather than direction, both NEU4-to-partner and partner-to-NEU4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEU4→partner) and Y-score (partner→NEU4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PDZD2 →	+3.847	+5.108	.001	.001	1	5
BREAST	SRRT →	+4.857	+4.297	.009	.009	1	4
LUNG_NSCLC_LUAD	EIF4G3 →	+5.000	+4.187	.008	.008	1	4
BLOOD_Leukemia	FAM83H →	+2.985	+3.548	<.001	<.001	1	4
BLOOD_Leukemia	LRRK2 →	+2.762	+3.111	<.001	<.001	1	4
LUNG_SCLC	FBH1 →	+5.502	+5.502	.003	.003	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,914 associations by consensus.

Exploration

NEU4 survival (RNA) · tumor vs normal (RNA) · all NEU4 data types