NELL1

Across TCGA patient cohorts, NELL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,379 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NELL1-associated proteins across cancer lineages are ARFGEF3_S2081, SCCPDH, and UPP1. Each is linked with NELL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NELL1-to-partner and partner-to-NELL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NELL1 versus ARFGEF3_S2081 in LUAD, with a Pearson correlation of 0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NELL1→partner) and Y-score (partner→NELL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ARFGEF3_S2081 →	+0.556	+1.468	<.001	<.001	3	4
HNSC	SCCPDH →	+0.403	+0.744	.001	.001	3	3
HNSC	UPP1 →	-0.744	-0.676	<.001	.005	3	3
LSCC	MAP1B_S1427 →	+1.536	+1.487	<.001	<.001	3	3
LSCC	MAP2 →	+0.674	+0.980	<.001	<.001	3	3
OV	UCHL1 →	+1.262	+1.463	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,379 associations by consensus.

NELL1 vs ARFGEF3_S2081 — LUAD

Explore this scatter interactively →