Across TCGA patient cohorts, NELFE RNA expression is significantly associated with the protein abundance of many other proteins, with 13,995 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NELFE-associated proteins across cancer lineages are DAXX, MCM3, and MCM6. Each is linked with NELFE in more than 7 cancer types. Because this analysis shows association rather than direction, both NELFE-to-partner and partner-to-NELFE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NELFE→partner) and Y-score (partner→NELFE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DAXX →	+0.397	+0.352	<.001	<.001	3	8
LSCC	MCM3 →	+0.835	+0.694	<.001	<.001	3	8
LSCC	MCM6 →	+0.865	+0.694	<.001	<.001	3	8
BRCA	MCM7 →	+0.748	+0.499	<.001	<.001	3	8
OV	CMTR1 →	+0.338	+0.634	<.001	<.001	3	7
OV	XPO5 →	+0.759	+0.784	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,995 associations by consensus.

Exploration

NELFE survival (RNA) · tumor vs normal (RNA) · all NELFE data types