NELFA

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NELFA mutation is significantly associated with the RNA expression of many other genes, with 582 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NELFA-associated genes across cancer lineages are RPL39P25, CDY10P, and LINC01732. Each is linked with NELFA in more than 1 cancer types. Because this analysis shows association rather than direction, both NELFA-to-partner and partner-to-NELFA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NELFA→partner) and Y-score (partner→NELFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRPL39P25 →+0.376+4.200<.001.00432
UCECCDY10P →+0.010+4.156<.001.00432
COADLINC01732 →+0.225+2.937.001.00731
COADOR7E11P →+0.109+3.843.002<.00131
COADMIR5580 →+0.817+3.543<.001.00131
COADRNA5-8SN3 →+0.805+4.557<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 582 associations by consensus.

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