Across TCGA pan-cancer cohorts, NEGR1-IT1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of NEGR1-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NEGR1-IT1 RNA is repressed in tumor relative to normal tissue. In most cancer types NEGR1-IT1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

KIRC are the cancer types where NEGR1-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NEGR1-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.021	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: NEGR1-IT1 RNA expression & survival · all NEGR1-IT1 data types