NEFH

Across TCGA patient cohorts, NEFH protein abundance is significantly associated with the RNA expression of many other genes, with 17,620 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NEFH-associated genes across cancer lineages are ADH1B, ABCB1, and DIO3. Each is linked with NEFH in more than 3 cancer types. Because this analysis shows association rather than direction, both NEFH-to-partner and partner-to-NEFH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEFH versus ADH1B in BRCA, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEFH→partner) and Y-score (partner→NEFH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ADH1B →	+1.855	+0.700	<.001	.001	3	4
UCEC	ABCB1 →	+1.024	+0.712	.001	<.001	3	4
GBM	DIO3 →	+0.807	+1.155	<.001	<.001	3	4
GBM	ASPA →	+1.046	+0.987	<.001	<.001	3	3
UCEC	C7 →	+1.988	+0.455	<.001	.002	3	3
GBM	PLP1 →	+3.089	+1.319	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,620 associations by consensus.

NEFH vs ADH1B — BRCA

Explore this scatter interactively →