NEDD8

Across TCGA cell cohorts, NEDD8 RNA expression is significantly associated with the RNA expression of many other genes, with 7,464 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NEDD8-associated genes across cancer lineages are PSMB5, NGDN, and MRPL52. Each is linked with NEDD8 in more than 19 cancer types. Because this analysis shows association rather than direction, both NEDD8-to-partner and partner-to-NEDD8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEDD8 versus PSMB5 in OESOPHAGUS, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEDD8→partner) and Y-score (partner→NEDD8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	PSMB5 →	+1.090	+0.936	<.001	<.001	3	20
OESOPHAGUS	NGDN →	+1.236	+1.201	<.001	<.001	3	19
OESOPHAGUS	MRPL52 →	+1.463	+1.447	<.001	<.001	3	19
STOMACH	C14orf119 →	+1.008	+0.906	.001	.008	2	18
OESOPHAGUS	DAD1 →	+1.214	+1.296	<.001	<.001	3	17
BONE	ERH →	+0.949	+0.682	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,464 associations by consensus.

NEDD8 vs PSMB5 — OESOPHAGUS

Explore this scatter interactively →