NECTIN1-AS1

Across TCGA patient cohorts, NECTIN1-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,389 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NECTIN1-AS1-associated proteins across cancer lineages are NECTIN1, NECTIN1_S422, and ERG_S81. Each is linked with NECTIN1-AS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NECTIN1-AS1-to-partner and partner-to-NECTIN1-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NECTIN1-AS1 versus NECTIN1 in LSCC, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NECTIN1-AS1→partner) and Y-score (partner→NECTIN1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NECTIN1 →	+0.463	+0.689	<.001	<.001	3	4
UCEC	NECTIN1_S422 →	+0.701	+1.081	<.001	<.001	3	4
OV	ERG_S81 →	-1.221	-0.091	<.001	.009	3	3
LSCC	PALM2AKAP2_S361 →	-0.761	-0.805	<.001	.001	3	3
PDAC	KRT5_S71 →	+2.800	+1.115	<.001	<.001	3	3
LSCC	PKP1 →	+1.228	+1.177	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,389 associations by consensus.

NECTIN1-AS1 vs NECTIN1 — LSCC

Explore this scatter interactively →