NEBL

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NEBL protein abundance is significantly associated with the RNA expression of many other genes, with 20,423 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NEBL-associated genes across cancer lineages are NPM1P30, MTND1P21, and EIF4BP2. Each is linked with NEBL in more than 7 cancer types. Because this analysis shows association rather than direction, both NEBL-to-partner and partner-to-NEBL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEBL versus NPM1P30 in UCEC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEBL→partner) and Y-score (partner→NEBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNPM1P30 →+1.676+1.346<.001<.00138
GBMMTND1P21 →+1.188+0.674<.001<.00138
GBMEIF4BP2 →+0.698+0.505<.001<.00137
BRCAFBXO5 →-0.921-0.620<.001<.00137
UCECCENPF →-1.213-0.803<.001.00637
BRCAKIF18A →-1.001-0.662<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,423 associations by consensus.

NEBL vs NPM1P30 — UCEC

Per-sample scatter of NEBL vs NPM1P30 in UCEC (Pearson r = 0.50).

Explore this scatter interactively →

Exploration