Q-omics provides the consensus-scored MTND1P21 profile across patient tissues and cancer cell-line models. MTND1P21 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in LUAD. Among the 18 cancer types available for tumor–normal comparison, MTND1P21 is differentially expressed in 8, with the highest sampling consensus in THCA. Additionally, MTND1P21 RNA expression shows 8,187 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight LUAD, THCA, and GBM as cancer lineages where MTND1P21 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MTND1P21 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MTND1P21 survival associations across molecular data types. MTND1P21 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MTND1P21 RNA expression–survival associations across cancer types. High MTND1P21 expression shows unfavorable associations in LUAD, LUSC, ACC, UCEC, ESCA and CHOL. The LUAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LUAD as the clearest survival context for MTND1P21 RNA expression.
This table summarizes MTND1P21 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for MTND1P21. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MTND1P21 shows lower tumor expression in THCA, KIRP, KIRC and LUSC and higher tumor expression in ESCA and STAD. The THCA box plot shows higher MTND1P21 RNA expression in normal versus tumor tissue (log2 FC = −0.156, t-test p < 0.001).
This table shows molecular features associated with MTND1P21 in patient tissues and cancer cell lines. In patient samples, MTND1P21 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
