NEBL-AS1

Across TCGA patient cohorts, NEBL-AS1 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEBL-AS1-associated genes across cancer lineages are RNU6-11P, RNU6-841P, and RNU6-110P. Each is linked with NEBL-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEBL-AS1-to-partner and partner-to-NEBL-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-11P grouped by NEBL-AS1-low versus NEBL-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEBL-AS1→partner) and Y-score (partner→NEBL-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-11P →	+0.582	+4.211	.004	.009	3	1
UCEC	RNU6-841P →	+0.513	+4.694	<.001	.007	3	1
UCEC	RNU6-110P →	+1.107	+4.326	<.001	.007	3	1
UCEC	RNU4-69P →	+0.805	+5.335	<.001	.003	3	1
UCEC	RBPJP6 →	+0.046	+6.049	<.001	.001	3	1
UCEC	LINC01005 →	+0.104	+5.038	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

RNU6-11P by NEBL-AS1 expression — UCEC

Explore this box plot interactively →