NEBL-AS1

Across TCGA pan-cancer cohorts, NEBL-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated NEBL-AS1 data layer compared with 1 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher NEBL-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated NEBL-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and KIRP show a favorable association.

KIRC, UCEC, and KIRP are the cancer types where NEBL-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	All	0.732	0.531	<.001	80	view →
UCEC	DFS	Quartile	II,III,IV	0.404	0.789	.001	60	view →
KIRP	OS	Median	All	0.936	0.829	.004	37	view →
LIHC	OS	Quartile	All	0.641	0.822	<.001	30	view →
MESO	OS	Median	All	0.475	0.290	.005	22	view →
OV	DFS	Tertile	III,IV	0.133	0.216	.018	18	view →
BLCA	OS	Quartile	IV	0.238	0.758	.004	15	view →
ACC	DFS	Median	IV	0.532	0.205	.012	11	view →
LUAD	OS	Quartile	All	0.887	0.767	.006	9	view →
COAD	OS	Median	III,IV	0.369	0.811	.002	8	view →
PAAD	DFS	Median	All	0.349	0.185	.021	7	view →
UVM	OS	Tertile	All	0.610	0.956	.002	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

NEBL-AS1–KIRC (OS)

Open the KIRC breakdown →