NEB

Across TCGA patient cohorts, NEB protein abundance is significantly associated with the RNA expression of many other genes, with 6,514 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NEB-associated genes across cancer lineages are ANK2, HSPB8, and ASB2. Each is linked with NEB in more than 3 cancer types. Because this analysis shows association rather than direction, both NEB-to-partner and partner-to-NEB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NEB versus ANK2 in HNSC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEB→partner) and Y-score (partner→NEB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ANK2 →	+1.191	+1.358	<.001	<.001	3	4
OV	HSPB8 →	+1.558	+1.088	<.001	.005	3	3
HNSC	ASB2 →	+0.972	+1.349	<.001	<.001	3	3
LUAD	CHRDL1 →	+1.145	+0.527	<.001	.004	3	3
HNSC	CASQ2 →	+2.358	+1.484	<.001	<.001	3	3
HNSC	NAPSB →	+1.080	+1.108	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,514 associations by consensus.

NEB vs ANK2 — HNSC

Explore this scatter interactively →