NEB

Across TCGA cell cohorts, NEB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,939 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NEB-associated GO terms across cancer lineages are Mitotic DNA integrity checkpoint signaling, RNA catabolic process, and Post-transcriptional gene silencing. Each is linked with NEB in more than 13 cancer types. Because this analysis shows association rather than direction, both NEB-to-partner and partner-to-NEB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic DNA integrity checkpoint signaling grouped by NEB-low versus NEB-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEB→partner) and Y-score (partner→NEB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitotic DNA integrity checkpoint signaling →	+0.110	+1.547	.008	<.001	3	14
LUNG_NSCLC_LUSC	RNA catabolic process →	+0.060	+1.071	.002	.004	3	14
BLOOD_Lymphoma	Post-transcriptional gene silencing →	+0.087	+0.773	<.001	<.001	3	13
SOFT_TISSUE	Nucleic acid catabolic process →	+0.055	+2.505	<.001	.002	3	13
LARGE_INTESTINE	Spliceosomal complex assembly →	+0.083	+1.232	<.001	<.001	3	13
SOFT_TISSUE	Regulation of DNA-templated transcription elongation →	+0.076	+2.602	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,939 associations by consensus.

Mitotic DNA integrity checkpoint signaling by NEB expression — BONE

Explore this box plot interactively →