NDUFS7

Across TCGA patient cohorts, NDUFS7 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFS7-associated genes across cancer lineages are ERK2, MSH2, and p90 RSK. Each is linked with NDUFS7 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFS7-to-partner and partner-to-NDUFS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by NDUFS7-low versus NDUFS7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS7→partner) and Y-score (partner→NDUFS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.197	+3.169	.034	.019	3	1
UCEC	MSH2 →	-0.328	-2.990	.003	.036	3	1
UCEC	p90 RSK →	+0.209	+2.331	.023	.019	3	1
UCEC	Rad50 →	-0.261	-2.459	.026	.020	3	1
UCEC	Caspase-7-cleavedD198 →	+1.039	+2.999	<.001	.035	3	1
UCEC	c-Jun_pS73 →	-0.172	-3.160	.025	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

ERK2 by NDUFS7 expression — UCEC

Explore this box plot interactively →