NDUFS2

Across TCGA patient cohorts, NDUFS2 mutation is significantly associated with the RNA expression of many other genes, with 2,286 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFS2-associated genes across cancer lineages are PRELID1P2, RN7SKP221, and RNU7-20P. Each is linked with NDUFS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFS2-to-partner and partner-to-NDUFS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRELID1P2 grouped by NDUFS2-low versus NDUFS2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS2→partner) and Y-score (partner→NDUFS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PRELID1P2 →	+0.091	+4.754	<.001	.005	3	2
BRCA	RN7SKP221 →	+0.065	+7.471	<.001	.008	3	2
LUAD	RNU7-20P →	+0.453	+4.798	.006	.006	3	2
LUAD	KYNUP2 →	+0.018	+5.315	<.001	.003	3	2
COAD	RNU6-933P →	+0.430	+4.484	.001	.002	3	2
COAD	TRAJ12 →	+1.428	+3.818	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,286 associations by consensus.

PRELID1P2 by NDUFS2 expression — HNSC

Explore this box plot interactively →