Q-omics provides the consensus-scored KYNUP2 profile across patient tissues and cancer cell-line models. KYNUP2 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in SKCM. Additionally, KYNUP2 RNA expression shows 5,934 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight SKCM, and STAD as cancer lineages where KYNUP2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes KYNUP2 survival associations across molecular data types. KYNUP2 RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

KYNUP2 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	12	SKCM (108)	view →

This table ranks reproducible KYNUP2 RNA expression–survival associations across cancer types. High KYNUP2 expression shows unfavorable associations in SKCM, ESCA, THCA, LIHC, KIRC and STAD. The SKCM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for KYNUP2 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	All	0.066	0.739	<.001	108	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
THCA	DFS	Tertile	II,III,IV	0.108	0.771	<.001	36	view →
LIHC	DFS	Tertile	All	0.099	0.555	.002	36	view →
KIRC	DFS	Tertile	II,III,IV	0.360	0.684	.006	36	view →
STAD	OS	Tertile	III,IV	0.262	0.534	.011	27	view →

Pink = unfavorable, green = favorable. all 12 lineages →

KYNUP2-SKCM (DFS)

Kaplan–Meier survival curve for KYNUP2 RNA expression in SKCM: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with KYNUP2 in patient tissues and cancer cell lines. In patient samples, KYNUP2 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,934	STAD (5714)	view →
RNA	3,098	DLBC (492)	view →