KYNUP2

Across TCGA patient cohorts, KYNUP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,934 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KYNUP2-associated GO terms across cancer lineages are Macromolecule deacylation, Positive regulation of ubiquitin-dependent protein catabolic process, and Regulation of cysteine-type endopeptidase activity. Each is linked with KYNUP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both KYNUP2-to-partner and partner-to-KYNUP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule deacylation grouped by KYNUP2-low versus KYNUP2-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KYNUP2→partner) and Y-score (partner→KYNUP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Macromolecule deacylation →	+0.111	+0.004	<.001	.007	2	7
LUSC	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.114	+0.002	<.001	.004	3	6
LUSC	Regulation of cysteine-type endopeptidase activity →	+0.106	+0.006	<.001	.001	3	6
ESCA	Regulation of nuclease activity →	+0.115	+0.021	<.001	.002	3	6
LUSC	Negative regulation of protein binding →	+0.096	+0.003	<.001	.003	2	7
ESCA	Alternative mRNA splicing, via spliceosome →	+0.119	+0.014	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,934 associations by consensus.

Macromolecule deacylation by KYNUP2 expression — LUSC

Explore this box plot interactively →