NDUFC1

Across TCGA patient cohorts, NDUFC1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. COAD shows the largest number of these associations.

The most reproducible NDUFC1-associated genes across cancer lineages are MIR634, RNU6-420P, and KRTAP4-7. Each is linked with NDUFC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFC1-to-partner and partner-to-NDUFC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR634 grouped by NDUFC1-low versus NDUFC1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFC1→partner) and Y-score (partner→NDUFC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR634 →	+0.504	+5.283	<.001	.006	3	1
COAD	RNU6-420P →	+0.841	+6.917	<.001	<.001	3	1
COAD	KRTAP4-7 →	+0.448	+5.693	<.001	.003	3	1
COAD	MIR5008 →	+0.520	+5.516	<.001	.004	3	1
COAD	MIR6780A →	+0.632	+5.080	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

MIR634 by NDUFC1 expression — COAD

Explore this box plot interactively →