NDUFB8

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NDUFB8 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible NDUFB8-associated genes across cancer lineages are LINC01810, RNA5SP93, and RN7SKP128. Each is linked with NDUFB8 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB8-to-partner and partner-to-NDUFB8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01810 grouped by NDUFB8-low versus NDUFB8-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB8→partner) and Y-score (partner→NDUFB8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCALINC01810 →+0.109+7.640<.001.00932
SKCMRNA5SP93 →+0.368+8.228<.001<.00132
COADRN7SKP128 →+0.538+7.741<.001.00932
UCECRAB11AP2 →+0.112+4.727<.001.00332
SKCMOR5K1 →+0.048+6.797<.001<.00132
UCECMIR4692 →+0.398+4.132<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

LINC01810 by NDUFB8 expression — BLCA

Box plot of LINC01810 in NDUFB8-low vs NDUFB8-high samples in BLCA.

Explore this box plot interactively →

Exploration