NDUFAF4

Across TCGA cell cohorts, NDUFAF4 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NDUFAF4-associated genes across cancer lineages are LIM2, USP26, and LCE1C. Each is linked with NDUFAF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFAF4-to-partner and partner-to-NDUFAF4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIM2 grouped by NDUFAF4-low versus NDUFAF4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFAF4→partner) and Y-score (partner→NDUFAF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LIM2 →	+0.035	+5.201	<.001	.006	3	1
BLOOD_Leukemia	USP26 →	+0.036	+5.201	<.001	.006	3	1
BLOOD_Leukemia	LCE1C →	+0.432	+4.922	.002	.009	3	1
BLOOD_Leukemia	PAGE3 →	+0.110	+5.969	<.001	.001	3	1
BLOOD_Leukemia	SLC5A8 →	+0.182	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TEX13A →	+0.062	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

LIM2 by NDUFAF4 expression — BLOOD_Leukemia

Explore this box plot interactively →