NDUFA10

Across TCGA patient cohorts, NDUFA10 mutation is significantly associated with the RNA expression of many other genes, with 2,611 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFA10-associated genes across cancer lineages are SENP3-EIF4A1, RNA5SP75, and CENPM. Each is linked with NDUFA10 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFA10-to-partner and partner-to-NDUFA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SENP3-EIF4A1 grouped by NDUFA10-low versus NDUFA10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFA10→partner) and Y-score (partner→NDUFA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SENP3-EIF4A1 →	+0.116	+1.829	<.001	.008	3	2
CESC	RNA5SP75 →	+0.565	+5.103	<.001	.008	3	2
UCEC	CENPM →	+0.520	+2.169	.009	.003	3	2
UCEC	PHF5A →	+0.608	+3.321	<.001	<.001	3	2
UCEC	NUP93 →	+0.398	+2.180	.006	.002	3	2
UCEC	TAF1C →	+0.490	+2.923	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,611 associations by consensus.

SENP3-EIF4A1 by NDUFA10 expression — UCEC

Explore this box plot interactively →