NDUFA10

Across TCGA pan-cancer cohorts, NDUFA10 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of NDUFA10’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where NDUFA10 RNA is repressed in tumor relative to normal tissue. In most cancer types NDUFA10 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and LIHC are the cancer types where NDUFA10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NDUFA10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	II,III,IV	−0.376	<.001	10	view →
KIRC	Male	II,III,IV	−0.598	<.001	8	view →
LIHC	Female	All	+0.478	<.001	8	view →
KICH	Female	II,III,IV	−0.749	<.001	7	view →
LUSC	Male	All	+0.418	<.001	7	view →
LUAD	Male	II,III,IV	+0.510	<.001	6	view →
CHOL	All	All	+1.101	<.001	5	view →
STAD	All	II,III,IV	+0.259	.025	4	view →
UCEC	All	III,IV	+0.382	.032	2	view →
KIRP	Male	All	−0.284	.020	2	view →
HNSC	Female	IV	−0.330	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

NDUFA10–THCA

Open the THCA breakdown →