NDP

Across TCGA patient cohorts, NDP protein abundance is significantly associated with the RNA expression of many other genes, with 13,540 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible NDP-associated genes across cancer lineages are DENND5B, NDNF, and NMU. Each is linked with NDP in more than 1 cancer types. Because this analysis shows association rather than direction, both NDP-to-partner and partner-to-NDP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDP versus DENND5B in BRCA, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDP→partner) and Y-score (partner→NDP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DENND5B →	+1.611	+2.120	<.001	.002	3	2
UCEC	NDNF →	+1.341	+1.491	<.001	<.001	3	2
BRCA	NMU →	-2.427	-1.625	<.001	.004	3	2
BRCA	CDCA3 →	-1.939	-1.857	.008	.001	3	2
UCEC	ABCG2 →	+1.139	+1.301	<.001	<.001	3	2
UCEC	EDA2R →	+1.194	+1.164	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,540 associations by consensus.

NDP vs DENND5B — BRCA

Explore this scatter interactively →