NCR2

Across TCGA patient cohorts, NCR2 mutation is significantly associated with the RNA expression of many other genes, with 384 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCR2-associated genes across cancer lineages are LINC02353, SETBP1-DT, and SNORD112. Each is linked with NCR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCR2-to-partner and partner-to-NCR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02353 grouped by NCR2-low versus NCR2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCR2→partner) and Y-score (partner→NCR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC02353 →	+0.093	+5.669	<.001	.003	3	2
SKCM	SETBP1-DT →	-0.451	-2.887	.003	.001	3	2
LUSC	SNORD112 →	+0.413	+5.309	<.001	.003	3	2
COAD	AP1B1P2 →	+0.983	+5.602	<.001	.004	3	2
SKCM	RNU6-527P →	+0.134	+2.662	<.001	.005	3	2
SKCM	RNU6-1056P →	+0.229	+2.073	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 384 associations by consensus.

LINC02353 by NCR2 expression — CESC

Explore this box plot interactively →