NCOA3

Across TCGA patient cohorts, NCOA3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,052 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NCOA3-associated genes across cancer lineages are MYBL2, TTI1, and E2F1. Each is linked with NCOA3 in more than 3 cancer types. Because this analysis shows association rather than direction, both NCOA3-to-partner and partner-to-NCOA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NCOA3 versus MYBL2 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA3→partner) and Y-score (partner→NCOA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYBL2 →	+1.405	+0.305	<.001	<.001	3	4
LUAD	TTI1 →	+0.471	+0.186	.001	<.001	3	4
UCEC	E2F1 →	+1.090	+0.165	<.001	.003	3	4
UCEC	CSE1L →	+0.700	+0.243	<.001	<.001	3	4
UCEC	TOP2A →	+1.193	+0.227	<.001	<.001	3	4
UCEC	TICRR →	+0.777	+0.206	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,052 associations by consensus.

NCOA3 vs MYBL2 — BRCA

Explore this scatter interactively →