NCMAP-DT

Across TCGA patient cohorts, NCMAP-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,073 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible NCMAP-DT-associated GO terms across cancer lineages are Bile acid metabolic process, Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway, and Regulation of glucose import. Each is linked with NCMAP-DT in more than 13 cancer types. Because this analysis shows association rather than direction, both NCMAP-DT-to-partner and partner-to-NCMAP-DT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bile acid metabolic process grouped by NCMAP-DT-low versus NCMAP-DT-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCMAP-DT→partner) and Y-score (partner→NCMAP-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Bile acid metabolic process →	+0.047	+0.175	<.001	<.001	3	14
STAD	Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway →	+0.053	+0.135	<.001	<.001	3	14
STAD	Regulation of glucose import →	+0.035	+0.121	<.001	<.001	3	14
ESCA	Signal peptide processing →	+0.046	+0.150	<.001	.002	3	13
ESCA	Protein quality control for misfolded or incompletely synthesized proteins →	+0.057	+0.216	<.001	<.001	3	13
ESCA	Peroxisome organization →	+0.043	+0.139	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,073 associations by consensus.

Bile acid metabolic process by NCMAP-DT expression — ESCA

Explore this box plot interactively →