NCMAP-DT

Across TCGA pan-cancer cohorts, NCMAP-DT RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated NCMAP-DT data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NCMAP-DT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated NCMAP-DT expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

HNSC, UCEC, and LUSC are the cancer types where NCMAP-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	III,IV	0.425	0.264	.006	79	view →
UCEC	DFS	Quartile	II,III,IV	0.916	0.734	.003	30	view →
LUSC	OS	Tertile	III,IV	0.508	0.781	.005	27	view →
SKCM	OS	Tertile	All	0.909	0.749	.016	18	view →
CHOL	DFS	Median	II,III,IV	0.690	0.151	.004	17	view →
DLBC	OS	Tertile	IV	0.367	0.897	.018	17	view →
CESC	DFS	Tertile	All	0.635	0.789	.006	16	view →
STAD	DFS	Tertile	IV	0.171	0.547	.007	15	view →
LAML	DFS	Tertile	All	0.688	0.344	.042	12	view →
SARC	DFS	Tertile	All	0.790	0.346	.031	12	view →
LIHC	DFS	Median	All	0.313	0.531	.002	12	view →
OV	OS	Median	II,III,IV	0.881	0.805	.013	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

NCMAP-DT–HNSC (DFS)

Open the HNSC breakdown →