NCF1C

Across TCGA patient cohorts, NCF1C mutation is significantly associated with the RNA expression of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCF1C-associated genes across cancer lineages are GAPDHP56, SPDYE9, and RNA5SP534. Each is linked with NCF1C in more than 1 cancer types. Because this analysis shows association rather than direction, both NCF1C-to-partner and partner-to-NCF1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDHP56 grouped by NCF1C-low versus NCF1C-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCF1C→partner) and Y-score (partner→NCF1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GAPDHP56 →	+0.153	+5.602	.001	<.001	3	2
UCEC	SPDYE9 →	+0.007	+4.242	<.001	.006	3	2
UCEC	RNA5SP534 →	+0.392	+3.920	<.001	<.001	3	1
UCEC	IKBKGP1 →	+0.122	+2.884	.001	.006	3	1
UCEC	MIR6781 →	+0.827	+3.043	<.001	.002	3	1
COAD	RNA5SP286 →	+0.603	+4.893	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

GAPDHP56 by NCF1C expression — COAD

Explore this box plot interactively →